Transplacental Transmission of Rubella Virus Infection in Rabbits

Transplacental transmission of rubella virus infection in rabbits.

Rabbits were inseminated artificially and inoculated 1 week later with rubella virus. The attenuated vaccine strain HPV-77 or strain 67-1127 which had been through 12 cell culture passages was used. Half of the rabbits in each group had been inoculated 1 month prior to insemination with the corresponding strain. Evidence of infection induced by either strain was obtained by immunofluorescence i...

Transplacental Transmission of Hepatitis B Virus in Mazandaran Province of Iran

Transplacental Transmission of Bluetongue Virus 8 in Cattle, UK

To determine whether transplacental transmission could explain overwintering of bluetongue virus in the United Kingdom, we studied calves born to dams naturally infected during pregnancy in 2007-08. Approximately 33% were infected transplacentally; some had compromised health. In all infected calves, viral load decreased after birth; no evidence of persistent infection was found.

Infection of rubella virus in pregnancy.

Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes

Zika virus (ZIKV) crosses the placenta and causes congenital disease. Here we develop an animal model utilizing direct ZIKV inoculation into the uterine wall of pregnant, immunocompetent mice to evaluate transplacental transmission. Intrauterine inoculation at embryonic day (E) 10, but not E14, with African, Asian or American strains of ZIKV reduces fetal viability and increases infection of pl...